Environmental and lifestyle exposures

1. Environmental and lifestyle exposures raise the risk of colorectal cancer in humans.

   “We propose that sporadic microsatellite-stable EOCRC and a subset of PCCRC represent sentinel manifestations of a broader, under-recognised process of exposure-related accelerated carcinogenesis.”

   Review

   Emerging exposure-driven accelerated colorectal carcinogenesis: a model with implications for screening colonoscopy effectiveness

   Gut·24 Aug 2026

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