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Engrailed-1

Engrailed-1 has been studied in 1 paper since 2023: none in people yet, 1 in animals. The research so far is in animals. The newest paper, Jul 6, 2023: “ENGRAILED-1 transcription factor has a paracrine neurotrophic activity on adult spinal α-motoneurons”.

Intervention

1 paper studies it1 findingUpdated

See all 1 papers on Engrailed-1

At a glance

The findings reach mice, none yet in people. 1 lab in 1 country.

Mice: a single group. Cells, worms or flies and humans: nothing yet.

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: Agence Nationale de la Recherche and 3 more
  • Animals1

What did studies of Engrailed-1 find?

1

Studies of Engrailed-1 measured one outcome, neurodegenerative disease.

Neurodegenerative disease

downin mice1

1 study

  1. Engrailed-1 protects against neurodegenerative disease in mice.

    “Intrathecal injection of ENGRAILED-1 leads to its specific internalization by spinal motoneurons and has long-lasting protective effects against neurodegeneration and weakness”

    Animalsspinal cord

    ENGRAILED-1 transcription factor has a paracrine neurotrophic activity on adult spinal α-motoneurons

    EMBO reports

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