Engage-hf

Engage-hf has been studied in 1 paper since 2026: 1 trial in people; 1 in the past year. The newest paper, Nov 8, 2026: “A Multicenter Randomized Controlled Trial of a Digital Health Intervention for Medication Optimization in Heart Failure: The ENGAGE-HF Trial Outcomes”.

Intervention

1 paper studies it2 findingsUpdated

1 new paper in 30 daysSee all 1 papers on engage-hf

At a glance

The findings reach people, from one lab or study. 1 lab.

“At 90 days, the adjusted MOS was significantly higher in the ENGAGE-HF group compared to the control group (83.7% vs. 74.0%, p = 0.010).”
A Multicenter Randomized Controlled Trial of a Digital Health Intervention for Medication Optimization in Heart Failure: The ENGAGE-HF Trial OutcomesCirculation. Heart failure2026doi:10.1161/circheartfailure.126.015192

None of its findings points the other way.

Humans: a single group. Cells, worms or flies and mice: nothing yet.
  • 1 lab
  • Funder: American Heart Association
  • Human trial1

Studies in people

1 study gave engage-hf to people and measured what changed.

What changedDesignPeopleSource

up: Increases medication optimization score83.7% vs. 74.0%; p = 0.010

no change: Has no effect on kansas City Cardiomyopathy Questionnaire Clinical Summary Score75.2 (SE 2.6) vs. 72.2 (SE 2.6); p = 0.40

Randomized trial90 days134 peopleRecently hospitalized patients with heart failure, LVEF <50%, and suboptimal guideline-directed medical therapyCirculation. Heart failure, Nov 8, 2026

What did studies of engage-hf find?

2

Studies of engage-hf measured 2 outcomes: kansas City Cardiomyopathy Questionnaire Clinical Summary Score and medication optimization score.

Kansas City Cardiomyopathy Questionnaire Clinical Summary Score

no changein humans1

1 study
  1. Engage-hf showed no clear effect on kansas City Cardiomyopathy Questionnaire Clinical Summary Score in humans (75.2 (SE 2.6) vs. 72.2 (SE 2.6); p = 0.40).

    “KCCQ-23 CSS at 90 days was 75.2 (SE 2.6) in the intervention group versus 72.2 (SE 2.6) in the control group (between-group p = 0.40).”

    Human trialrecently hospitalized patients with heart failure, LVEF <50%, and suboptimal guideline-directed medical therapy; compared with usual carepatient-facing mobile app and clinician dashboard90 daysn = 134

    A Multicenter Randomized Controlled Trial of a Digital Health Intervention for Medication Optimization in Heart Failure: The ENGAGE-HF Trial Outcomes

    Circulation. Heart failure

Medication optimization score

upin humans1

1 study
  1. Engage-hf increases medication optimization score in humans (83.7% vs. 74.0%; p = 0.010).

    “At 90 days, the adjusted MOS was significantly higher in the ENGAGE-HF group compared to the control group (83.7% vs. 74.0%, p = 0.010).”

    Human trialrecently hospitalized patients with heart failure, LVEF <50%, and suboptimal guideline-directed medical therapy; compared with usual carepatient-facing mobile app and clinician dashboard90 daysn = 134

    A Multicenter Randomized Controlled Trial of a Digital Health Intervention for Medication Optimization in Heart Failure: The ENGAGE-HF Trial Outcomes

    Circulation. Heart failure

More on Medication optimization score

Latest

Dec 2025: 0Jan 2026: 0Feb 2026: 0Mar 2026: 0Apr 2026: 0May 2026: 0Jun 2026: 0Jul 2026: 0Aug 2026: 0Sep 2026: 0Oct 2026: 0Nov 2026: 11 paper in 12 months