Early-life exercise training

1. Early-life exercise training extends lifespan in flies.

   “the combination of apoLppRNAi and ELET extended the average lifespan of flies.”

   Model organismscombined with apolpp knockdown

   Early Life Exercise Training and Inhibition of Apolipoprotein B Expression to Improve Age-Related Arrhythmias and Prolong the Average Lifespan in Drosophila

   Preprints.org·Mar 29, 2022Preprint

2. Early-life exercise training has no effect on lifespan in flies.

   “Although treatment of apoLppRNAi and ELET alone had no significant effect on lifespan”

   Model organismsearly-life exercise training alone

   Early Life Exercise Training and Inhibition of Apolipoprotein B Expression to Improve Age-Related Arrhythmias and Prolong the Average Lifespan in Drosophila

   Preprints.org·Mar 29, 2022Preprint

1. Early-life exercise training decreases apolpp mRNA expression in flies.

   “ELET can also reduce the expression of apoLpp mRNA in aged flies”

   Model organisms

   Early Life Exercise Training and Inhibition of Apolipoprotein B Expression to Improve Age-Related Arrhythmias and Prolong the Average Lifespan in Drosophila

   Preprints.org·Mar 29, 2022Preprint

More on Apolpp mRNA expression

1. Early-life exercise training protects against arrhythmias in flies.

   “apoLppRNAi and ELET are sufficient to resist age-induced arrhythmias”

   Model organismsage-induced arrhythmiasheart

   Early Life Exercise Training and Inhibition of Apolipoprotein B Expression to Improve Age-Related Arrhythmias and Prolong the Average Lifespan in Drosophila

   Preprints.org·Mar 29, 2022Preprint

More on Arrhythmias