DLL1 + FLT3L + IL-7 mrna
1 paper3 findings
- 1 lab in 1 country
- Animals1
Outcomes
3Peptide vaccine response
upin mice1
1 study
Peptide vaccine response
upin mice1
DLL1 + FLT3L + IL-7 mrna improves peptide vaccine response in mice.
“Treatment with these mRNAs improved peptide vaccine responses”
AnimalsmRNA delivery to hepatocytes
Transient hepatic reconstitution of trophic factors enhances aged immunity
Nature17 Dec 2025
Antitumour immunity
upin mice1
1 study
Antitumour immunity
upin mice1
DLL1 + FLT3L + IL-7 mrna improves antitumour immunity in mice.
“Treatment with these mRNAs improved peptide vaccine responses and restored antitumour immunity in aged mice by increasing tumour-specific CD8+ infiltration and clonal diversity”
AnimalsmRNA delivery to hepatocytes
Transient hepatic reconstitution of trophic factors enhances aged immunity
Nature17 Dec 2025
Thymopoiesis
upin mice1
1 study
Thymopoiesis
upin mice1
DLL1 + FLT3L + IL-7 mrna increases thymopoiesis in mice.
“expanded common lymphoid progenitors, boosted de novo thymopoiesis without affecting haematopoietic stem cell (HSC) composition, and replenished T cells while enhancing dendritic cell abundance and function.”
AnimalsmRNA delivery to hepatocytes
Transient hepatic reconstitution of trophic factors enhances aged immunity
Nature17 Dec 2025