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Dietary yeast restriction

Intervention

1 paper2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

  • 1 lab in 1 country
  • Funders: Biotechnology and Biological Sciences Research Council and 1 more
  • Model organisms1

Outcomes

2

Mortality rate

downin flies1

1 study

  1. Dietary yeast restriction decreases mortality rate in flies.

    “Reduction of either dietary yeast or sugar can reduce mortality and extend life span”

    Model organisms

    Calories do not explain extension of life span by dietary restriction in Drosophila

    PLoS biology31 May 2005

Lifespan

upin flies1

1 study

  1. Dietary yeast restriction extends lifespan in flies.

    “Reduction of either dietary yeast or sugar can reduce mortality and extend life span”

    Model organisms

    Calories do not explain extension of life span by dietary restriction in Drosophila

    PLoS biology31 May 2005

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