Dietary magnesium deficiency
Dietary magnesium deficiency has been studied in 3 papers since 2011: 1 trial in people, 1 in animals, 1 review; 2 in the past year. The newest paper, Mar 1, 2026: “Magnesium Deficiency Accelerates Gut Aging and Increases Susceptibility to Colitis”.
3 papers study it5 findingsUpdated
See all 3 papers on dietary magnesium deficiency
At a glance
The findings reach people, from one lab or study. 2 independent labs in 2 countries.
“Consuming less than the EAR was associated with a significantly higher BMI and plasma C-reactive protein (CRP) concentration.”
None of its findings points the other way.
- 2 independent labs in 2 countries
- Funders: China Postdoctoral Science Foundation and 6 more
- Human trial1
- Animals1
What did studies of dietary magnesium deficiency find?
4Studies of dietary magnesium deficiency measured 4 outcomes, among them Adhesion complex stability, colitis severity and gut aging.
Adhesion complex stability
downin mice1
1 study
Adhesion complex stability
downin mice1
Dietary magnesium deficiency decreases adhesion complex stability in mice (dietary Mg deficiency; multi-omics analysis).
“dietary Mg deficiency reshapes the phosphoproteome and N-glycoproteome, destabilizing adhesion complexes”
Animalsdietary Mg deficiency; multi-omics analysis
Magnesium Deficiency Accelerates Gut Aging and Increases Susceptibility to Colitis
Aging cell
Colitis severity
upin mice1
1 study
Colitis severity
upin mice1
Dietary magnesium deficiency increases colitis severity in mice (dietary restriction).
“Functional studies demonstrated that Mg restriction accelerates gut aging in old but not in young mice and aggravates colitis severity.”
Animalsdietary restrictiongut
Magnesium Deficiency Accelerates Gut Aging and Increases Susceptibility to Colitis
Aging cell
Gut aging
upin mice1
1 study
Gut aging
upin mice1
Dietary magnesium deficiency increases gut aging in mice (dietary restriction; old mice compared with young mice).
“Functional studies demonstrated that Mg restriction accelerates gut aging in old but not in young mice and aggravates colitis severity.”
Animalsdietary restriction; old mice compared with young micegut
Magnesium Deficiency Accelerates Gut Aging and Increases Susceptibility to Colitis
Aging cell
Inflammation
upin humans1
1 study
Inflammation
upin humans1
Dietary magnesium deficiency induces inflammation in humans (long term magnesium deficiency).
“long term deficiency can lead to chronic inflammation, a problem being faced by many adults worldwide.”
Reviewlong term magnesium deficiency
Pakistan Journal of Medical & Cardiological Review
What is dietary magnesium deficiency linked with?
1Studies link dietary magnesium deficiency with C-reactive protein.
C-reactive protein
upin humans1
1 study
C-reactive protein
upin humans1
Dietary magnesium deficiency is associated with C-reactive protein in humans (dietary magnesium < EAR).
“Consuming less than the EAR was associated with a significantly higher BMI and plasma C-reactive protein (CRP) concentration.”
Human trialdietary magnesium < EAR
Magnesium research