Dendrobium nobile alkaloids
Dendrobium nobile alkaloids has been studied in 2 papers since 2022: none in people yet, 2 in animals. The research so far is in animals. The newest paper, May 6, 2023: “Proteomic analysis of anti-aging effects of Dendrobium nobile Lindl. alkaloids in aging-accelerated SAMP8 mice”.
2 papers study it5 findingsUpdated
None of its findings points the other way.
- 1 lab in 1 country
- Funder: Guizhou Provincial Science and Technology Department
- Animals2
What did studies of Dendrobium nobile alkaloids find?
3Studies of Dendrobium nobile alkaloids measured 3 outcomes; the most studied are neuron loss (2 studies), cognitive function (2) and aberrant protein/gene expression (1).
Neuron loss
downin mice2
2 studies
Neuron loss
downin mice2
Dendrobium nobile alkaloids decrease neuron loss in mice.
“The cognitive deficits and neuron loss in hippocampus and cortex of aged SAMP8 mice were improved by DNLA.”
Animalsin aged SAMP8 micealkaloidshippocampus and cortex20 and 40 mg/kg
Experimental gerontology
Dendrobium nobile alkaloids decrease neuron loss in mice.
“The cognitive deficits and neuron loss in hippocampus and cortex of aged SAMP8 mice were improved by DNLA.”
AnimalsAged SAMP8 micealkaloidsHippocampus and cortexFrom ages 6 to 10 months
Preprints.orgPreprint
Cognitive function
upin mice2
2 studies
Cognitive function
upin mice2
Dendrobium nobile alkaloids improve cognitive function in mice.
“The cognitive deficits and neuron loss in hippocampus and cortex of aged SAMP8 mice were improved by DNLA.”
Animalsin aged SAMP8 micealkaloidshippocampus and cortex20 and 40 mg/kg
Experimental gerontology
Dendrobium nobile alkaloids improve cognitive function in mice.
“Thus, DNLA improved cognitive dysfunction and ameliorated neuronal injury in aged SAMP8 mice, and attenuated aberrant protein/gene expressions.”
AnimalsAged SAMP8 micealkaloidsFrom ages 6 to 10 months
Preprints.orgPreprint
Aberrant protein/gene expression
downin mice1
1 study
Aberrant protein/gene expression
downin mice1
Dendrobium nobile alkaloids decrease aberrant protein/gene expression in mice.
“Thus, DNLA improved cognitive dysfunction and ameliorated neuronal injury in aged SAMP8 mice, and attenuated aberrant protein/gene expressions.”
AnimalsAged SAMP8 micealkaloidsHippocampusFrom ages 6 to 10 months
Preprints.orgPreprint