Cytoskeletal drugs
Cytoskeletal drugs has been studied in 2 papers since 2023: none in people yet, 2 in animals. The research so far is in animals. The newest paper, Oct 25, 2024: “Accumulation of F-actin drives brain aging and limits healthspan in Drosophila”.
2 papers study it2 findingsUpdated
None of its findings points the other way.
- 1 lab in 1 country
- Funders: National Institute on Aging and 5 more
- Model organisms2
What did studies of Cytoskeletal drugs find?
1Studies of Cytoskeletal drugs measured 1 outcome; the most studied are autophagy (2 studies).
Autophagy
upin flies2
2 studies
Autophagy
upin flies2
Cytoskeletal drugs activate autophagy in flies.
“disrupting actin polymerization in aged animals with cytoskeletal drugs restores brain autophagy to youthful levels”
Model organismsbrain
Accumulation of F-actin drives brain aging and limits healthspan in Drosophila
Nature communications
Cytoskeletal drugs activate autophagy in flies.
“disrupting actin polymerization in aged animals with cytoskeletal drugs restores brain autophagy to youthful levels”
Model organismsDisruption of actin polymerizationbrain
Accumulation of F-actin drives brain aging and limits healthspan in Drosophila
Research squarePreprint