AgingResearch.NewsJoin free

Cytidine analogs

Intervention

2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

  • 1 lab in 1 country
  • Funders: Biotechnology and Biological Sciences Research Council and 4 more
  • 2 of 2 findings with company ties

Outcomes

2

Transposable element activity

upin O. fusiformis1

1 study

  1. Cytidine analogs activate transposable element activity in O. fusiformis.

    “reducing 5mC levels with cytidine analogs during early development impairs normal embryogenesis and reactivates TEs in the annelid Owenia fusiformis.”

    Model organismsearly development

    Annelid methylomes reveal ancestral developmental and aging-associated epigenetic erosion across Bilateria

    Genome biologyAug 1, 2024

More on Transposable element activity

Embryogenesis

downin O. fusiformis1

1 study

  1. Cytidine analogs impair embryogenesis in O. fusiformis.

    “reducing 5mC levels with cytidine analogs during early development impairs normal embryogenesis”

    Model organismsearly development

    Annelid methylomes reveal ancestral developmental and aging-associated epigenetic erosion across Bilateria

    Genome biologyAug 1, 2024