Cumulative social disadvantage

Cumulative social disadvantage decreases reproductive lifespan in humans (β=-3.06, 95% CI: -3.92 to -2.19, P<0.001).

“higher cumulative social disadvantage was significantly associated with a shorter reproductive lifespan (β=-3.06, 95% CI: -3.92 to -2.19, P<0.001).”

Humansfemalesn = 8,576

Cumulative social determinants of health and reproductive lifespan among US women: a NHANES 1999-2018 analysis

Menopause (New York, N.Y.)·Jul 14, 2026

Cumulative social disadvantage decreases HALex score in humans (β = −0.01; 95% CI [−0.01, −0.01]).

“A unit increase in SDoH index was associated with 0.01 decrease in HALex score (β = −0.01; 95% CI [−0.01, −0.01])”

Humans51.7% womensn = 156,182

Cumulative Social Disadvantage and Health-Related Quality of Life: National Health Interview Survey 2013-2017

medRxiv·Aug 22, 2022Preprint

Cumulative social disadvantage raises the risk of poor HALex in humans (OR = 1.14; 95% CI [1.14, 1.15]).

“and 14% higher odds of poor HALex (odds ratio, OR = 1.14; 95% CI [1.14, 1.15]).”

Humans51.7% womensn = 156,182

Cumulative Social Disadvantage and Health-Related Quality of Life: National Health Interview Survey 2013-2017

medRxiv·Aug 22, 2022Preprint