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CTX0E03 cell therapy

Intervention

1 paper2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

  • 1 lab in 1 country
  • Funder: National Science Council
  • 2 of 2 findings with company ties
  • Animals1

Outcomes

2

Immature neurons

upin rats1

1 study

  1. CTX0E03 cell therapy increases immature neurons in rats.

    “The acute treatment also led to an increased number of immature neurons as demonstrated by immunohistochemical staining for the immature neuronal marker doublecortin.”

    Animalsintraventricular implantationdentate gyrus

    Increased neuronal proliferation in the dentate gyrus of aged rats following neural stem cell implantation

    Stem cells and development1 Feb 2010

Endogenous neural progenitor cell proliferation

upin rats1

1 study

  1. CTX0E03 cell therapy increases endogenous neural progenitor cell proliferation in rats.

    “Bromodeoxyuridine staining demonstrated significantly increased proliferation in the SGZ.”

    Animalsintraventricular implantationdentate gyrus subgranular zone

    Increased neuronal proliferation in the dentate gyrus of aged rats following neural stem cell implantation

    Stem cells and development1 Feb 2010

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