Comorbidity burden
Comorbidity burden has been studied in 3 papers since 2018: 3 observational studies in people; 1 in the past year. The newest paper, Apr 23, 2026: “Comorbidity burden and survival in patients with idiopathic pulmonary fibrosis: a real-world cohort study”.
3 papers study it3 findingsUpdated
“Increasing comorbidity burden was similarly associated with increased risk of death and long-term care placement”
None of its findings points the other way.
- 2 independent labs in 2 countries
- Funders: Alberta Health services and 3 more
- Humans3
What is Comorbidity burden linked with?
2Studies link Comorbidity burden with 2 measures, most often mortality (2 studies) and end-stage renal disease (1).
Mortality
upin humans2
2 studies
Mortality
upin humans2
Comorbidity burden is linked with a higher risk of mortality in humans (multivariable Cox analysis) (log-rank P < 0.001 for ≥2 vs 0–1 comorbidities).
“higher comorbidity burden was independently associated with increased mortality”
Humansmultivariable Cox analysis
Heart & lung : the journal of critical care
Comorbidity burden is linked with a higher risk of mortality in humans.
“Increasing comorbidity burden was similarly associated with increased risk of death and long-term care placement”
Humans
A population-based cohort study defines prognoses in severe chronic kidney disease
Kidney international
End-stage renal disease
downin humans1
1 study
End-stage renal disease
downin humans1
Comorbidity burden is linked with a lower risk of end-stage renal disease in humans.
“Increasing comorbidity burden was similarly associated with increased risk of death and long-term care placement but reduced the likelihood of ESRD”
Humans
A population-based cohort study defines prognoses in severe chronic kidney disease
Kidney international