Colorectal cancer screening

Intervention4 papers8 findings

A human study links colorectal cancer screening to greater detection of stage I, T1 and node-negative tumours. Another reports higher colorectal cancer risk among high-risk non-attenders; reviews describe reduced colorectal cancer incidence and mortality with screening.

Humans3

Outcomes

Colorectal cancer

downin humans1

1 study

Colorectal cancer screening decreases colorectal cancer in humans.
Reviewnational roll-out of Programme Svit
Why Organised Cancer Screening Works: Lessons from Slovenia and the Next Phase of Evidence-Based Implementation · Zdravstveno varstvo · 1 Sep 2026

Colorectal cancer →

N0 colorectal cancer detection

upin humans1Low certainty

1 study

Colorectal cancer screening increases N0 colorectal cancer detection in humans (2.03-fold higher odds).
Humans
The Association of FIT-Based Colorectal Cancer Screening with Earlier Disease Detection: The Romanian Experience · Cancers · 31 Aug 2026

T1 colorectal tumor detection

upin humans1Low certainty

1 study

Colorectal cancer screening increases T1 colorectal tumor detection in humans (6.34-fold higher odds).
Humans
The Association of FIT-Based Colorectal Cancer Screening with Earlier Disease Detection: The Romanian Experience · Cancers · 31 Aug 2026

Stage I colorectal cancer detection

upin humans1Low certainty

1 study

Colorectal cancer screening increases stage I colorectal cancer detection in humans (2.76-fold higher odds).
Humans
The Association of FIT-Based Colorectal Cancer Screening with Earlier Disease Detection: The Romanian Experience · Cancers · 31 Aug 2026

Mortality

downin humans1

1 study

Colorectal cancer screening decreases mortality in humans.
Review
Improving Adherence to Colorectal Cancer Screening Among Underserved Populations: Barriers and Strategies · Gastrointestinal endoscopy clinics of North America · 10 Jul 2026

Associations

Colorectal cancer

upin humans1downin humans1HR 2.79Low certainty

2 studies

Colorectal cancer screening is associated with colorectal cancer in humans (HR 2.79, 95% CI 2.39-3.25).
Humansin high-risk non-attenders
Long-term effectiveness of a two-step colorectal cancer screening strategy and risk of colorectal cancer after polypectomy · Chinese journal of cancer research = Chung-kuo yen cheng yen chiu · 30 Aug 2026
Colorectal cancer screening lowers the risk of colorectal cancer in humans.
Review
Improving Adherence to Colorectal Cancer Screening Among Underserved Populations: Barriers and Strategies · Gastrointestinal endoscopy clinics of North America · 10 Jul 2026

Colorectal cancer →

Colorectal cancer mortality

downin humans1Low certainty

1 study

Colorectal cancer screening lowers the risk of colorectal cancer mortality in humans.
Review
Barriers to Diagnostic Colonoscopy After a Positive Stool-Based Screening Test: A Scoping Review · Cancer prevention research (Philadelphia, Pa.) · 28 Aug 2026

Funding

National Cancer InstituteUS$8.7mNational Institute on Minority Health and Health DisparitiesUS$3.1mNational Institute on AgingUS$695k17 grants since 2021