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Circadian phase shift

Exposure

1 paper1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funder: National Heart, Lung, and Blood Institute
  • Animals1

Outcomes

1

Lifespan

upin M. auratus1

1 study

  1. Circadian phase shift extends lifespan in M. auratus.

    “this effect was eliminated when mutants experienced 8-h phase shifts every second week, to which they rapidly re-entrained.”

    Animalsin cardiomyopathic duper hamstersevery second week

    The duper mutation reveals previously unsuspected functions of Cryptochrome 1 in circadian entrainment and heart disease

    Proceedings of the National Academy of Sciences of the United States of America5 Aug 2022

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