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Cigarette sidestream smoke extract

Intervention

1 paper2 findings

  • Cells1

Outcomes

2

DNA damage response

upin human cells1

1 study

  1. Cigarette sidestream smoke extract increases DNA damage response in human cells.

    “Double strand breaks (DSBs) formation was detected in CSS-treated cells, indicating DSBs could be the cause for the CSS-induced cellular senescence.”

    Cellsin CSS-treated ASF-4-1 cells

    Cigarette sidestream smoke-induced cellular senescence and the protective role of histone H2AX

    Toxicology in vitro : an international journal published in association with BIBRAApr 24, 2025

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Cellular senescence

upin human cells1

1 study

  1. Cigarette sidestream smoke extract induces cellular senescence in human cells.

    “We exposed normal human skin diploid fibroblast ASF-4-1 to cigarette sidestream smoke (CSS) extract and successfully induced premature senescence.”

    Cellsin normal human skin diploid fibroblast ASF-4-1 cells

    Cigarette sidestream smoke-induced cellular senescence and the protective role of histone H2AX

    Toxicology in vitro : an international journal published in association with BIBRAApr 24, 2025

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