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Exercise + cognitive training + cholecalciferol

Intervention

1 paper studies it1 finding

Across all fields, 1 paper: 1 trial in people

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: Canadian Institutes of Health Research and 2 more
  • Human trial1

Outcomes

1

Functional brain connectivity

upin humans1

1 study

  1. Exercise + cognitive training + cholecalciferol increases functional brain connectivity in humans (p-FDR < 0.01).

    “and all three interventions combined (model four; p-FDR = < 0.01) demonstrated an increase in FBC between regions of the Default-Mode Network (i.e., hippocampus and angular gyrus).”

    Human trialmild cognitive impairmentbrain20-weeksn = 120

    Combining exercise with cognitive training and vitamin D₃ to improve functional brain connectivity (FBC) in older adults with mild cognitive impairment (MCI). Results from the SYNERGIC trial

    GeroScience

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