CHIR99021 + sonic hedgehog
CHIR99021 + sonic hedgehog has been studied in 1 paper since 2017: none in people yet, 1 in animals. The research so far is in animals. The newest paper, Jun 22, 2017: “Induced Pluripotent Stem Cell-Derived Dopaminergic Neurons from Adult Common Marmoset Fibroblasts”.
1 paper studies it1 findingUpdated
See all 1 papers on CHIR99021 + sonic hedgehog
At a glance
The findings reach cells, none yet in people. 1 lab in 1 country.
- 1 lab in 1 country
- Funders: Division of Graduate Education and 4 more
- Animals1
What did studies of CHIR99021 + sonic hedgehog find?
1Studies of CHIR99021 + sonic hedgehog measured one outcome, ventralized midbrain dopaminergic phenotype.
Ventralized midbrain dopaminergic phenotype
upin marmoset cells1
1 study
Ventralized midbrain dopaminergic phenotype
upin marmoset cells1
CHIR99021 + sonic hedgehog induces ventralized midbrain dopaminergic phenotype in marmoset cells after dual-SMAD inhibition-based neural differentiation.
“patterned the cells toward a ventralized midbrain dopaminergic phenotype, confirmed by expression of FOXA2, OTX2, EN-1, and tyrosine hydroxylase”
Cellsafter dual-SMAD inhibition-based neural differentiation12 and 16 days
Induced Pluripotent Stem Cell-Derived Dopaminergic Neurons from Adult Common Marmoset Fibroblasts
Stem cells and development