Childhood neighborhood socioeconomic position

Exposure

1 paper4 findings

  • 1 lab in 1 country
  • Humans1

Outcomes

1

Aβ42:40 ratio

no changein humans1

1 study
  1. Childhood neighborhood socioeconomic position has no effect on Aβ42:40 ratio in humans.

    “The AB42/40 ratio at midlife and late life was comparable across the childhood nSEP tertiles.”

    Humansn = 1,362

    Childhood neighborhood socioeconomic position and levels of plasma markers of Alzheimer's disease pathology and neurodegeneration in adulthood; the Atherosclerosis Risk in Communities Study

    AAIC 2025 abstract7 Jan 2026

More on Aβ42:40 ratio

Associations

3

GFAP

downin humans1

1 study
  1. Childhood neighborhood socioeconomic position is associated with GFAP in humans.

    “After covariate adjustment, midlife pTau181, NfL and GFAP concentrations were inversely associated with childhood nSEP”

    Humansn = 1,362

    Childhood neighborhood socioeconomic position and levels of plasma markers of Alzheimer's disease pathology and neurodegeneration in adulthood; the Atherosclerosis Risk in Communities Study

    AAIC 2025 abstract7 Jan 2026

More on GFAP

NfL

downin humans1

1 study
  1. Childhood neighborhood socioeconomic position is associated with NfL in humans (p-trend=0.05).

    “The association was marginally statistically significant for NfL ( p ‐trend=0.05).”

    Humansn = 1,362

    Childhood neighborhood socioeconomic position and levels of plasma markers of Alzheimer's disease pathology and neurodegeneration in adulthood; the Atherosclerosis Risk in Communities Study

    AAIC 2025 abstract7 Jan 2026

More on NfL

pTau-181

downin humans1

1 study
  1. Childhood neighborhood socioeconomic position is associated with pTau-181 in humans.

    “After covariate adjustment, midlife pTau181, NfL and GFAP concentrations were inversely associated with childhood nSEP”

    Humansn = 1,362

    Childhood neighborhood socioeconomic position and levels of plasma markers of Alzheimer's disease pathology and neurodegeneration in adulthood; the Atherosclerosis Risk in Communities Study

    AAIC 2025 abstract7 Jan 2026

More on pTau-181

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