Carnosine + taurocholic acid + inosine + l-histidine + n-acetylneuraminic acid

1 paper2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

1 lab in 1 country

Funder: National Natural Science Foundation of China

Model organisms1

Outcomes

Healthspan

upin worms1

1 study

Carnosine + taurocholic acid + inosine + l-histidine + n-acetylneuraminic acid improves healthspan in worms.
“demonstrates that a formula containing five of these metabolites (carnosine, taurocholic acid, inosine, L-Histidine and N-acetylneuraminic acid) significantly extends both lifespan and healthspan in C. elegans.”
Model organismsformula containing five metabolites
Human Umbilical Cord Plasma Metabolomics Uncover Potential Metabolites for Combating Aging
Aging cell26 Nov 2025

Lifespan

upin worms1

1 study

Carnosine + taurocholic acid + inosine + l-histidine + n-acetylneuraminic acid extends lifespan in worms.
“demonstrates that a formula containing five of these metabolites (carnosine, taurocholic acid, inosine, L-Histidine and N-acetylneuraminic acid) significantly extends both lifespan and healthspan in C. elegans.”
Model organismsformula containing five metabolites
Human Umbilical Cord Plasma Metabolomics Uncover Potential Metabolites for Combating Aging
Aging cell26 Nov 2025

Latest

1 in 12 months

Aging Cell27 Nov

Human Umbilical Cord Plasma Metabolomics Uncover Potential Metabolites for Combating Aging

Experiments in wormsInterventions

Paper

Carnosine + taurocholic acid + inosine + l-histidine + n-acetylneuraminic acid

Outcomes

Latest

Human Umbilical Cord Plasma Metabolomics Uncover Potential Metabolites for Combating Aging

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