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Carfilzomib

Intervention

1 paper1 finding

PubChemChEBI

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

About aging: trials about aging, of every trial that tests the drug for any use.

  • 1 lab in 1 country
  • 11 trials, none about aging
  • Funders: Fundamental Research Funds for the Central Universities and 2 more
  • Animals1

Outcomes

1

Endothelial dysfunction

downin mice1

1 study

  1. Carfilzomib prevents endothelial dysfunction in mice.

    “both Thonningianin A and Carfilzomib efficiently restored the GPR35-TRPV4 interaction, preventing endothelial dysfunction and vasodilation impairment”

    Animalsmesenteric arteries

    Investigating the Role of TRPV4 and GPR35 Interaction in Endothelial Dysfunction in Aging Mice

    Aging cellJan 2, 2025

More on Endothelial dysfunction

Development

Companies
  • Regeneron PharmaceuticalsPhase 3relapsed and/or refractory multiple myeloma

Trial sponsors

Latest

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