Candidate compounds

Candidate compounds extend lifespan in mice.

“Notably, most compounds that extended lifespan were effective primarily or exclusively in male mice.”

ReviewMost lifespan-extending compounds tested by the ITP were effective primarily or exclusively in malesmales

Sex as a major determinant of pro-longevity drug efficacy: a review of two decades of the NIA Interventions Testing Program

The journals of gerontology. Series A, Biological sciences and medical sciences·24 Jul 2025