Caloric restriction gut microbiota

Caloric restriction gut microbiota has been studied in 1 paper since 2022: none in people yet, 1 in animals. The research so far is in animals. The newest paper, Apr 4, 2022: “Effects of caloric restriction on the gut microbiome are linked with immune senescence”.

Intervention

1 paper studies it4 findingsUpdated

  • 1 lab in 1 country
  • Funders: Berlin Institute of Health and others
  • Animals1

What did studies of Caloric restriction gut microbiota find?

4

Studies of Caloric restriction gut microbiota measured 4 outcomes; the most studied are memory B-cells (1 study), effector memory CD8+ T-cells (1) and glucose tolerance (1).

Memory B-cells

downin mice1

1 study
  1. Caloric restriction gut microbiota decreases memory B-cells in mice.

    “Finally, the CalRes-associated microbiota reduced the levels of intestinal effector memory CD8+ T cells, intestinal memory B cells, and hepatic effector memory CD4+ and CD8+ T cells.”

    Animalscolon

    Effects of caloric restriction on the gut microbiome are linked with immune senescence

    Microbiome

More on Memory B-cells

Effector memory CD8+ T-cells

downin mice1

1 study
  1. Caloric restriction gut microbiota decreases effector memory CD8+ T-cells in mice.

    “Finally, the CalRes-associated microbiota reduced the levels of intestinal effector memory CD8+ T cells, intestinal memory B cells, and hepatic effector memory CD4+ and CD8+ T cells.”

    Animalscolon

    Effects of caloric restriction on the gut microbiome are linked with immune senescence

    Microbiome

More on Effector memory CD8+ T-cells

Glucose tolerance

upin mice1

1 study
  1. Caloric restriction gut microbiota improves glucose tolerance in mice.

    “Transplantation of CalRes-microbiota into mice decreased their body fat accumulation and improved glucose tolerance compared to AdLib-microbiota recipients.”

    Animalscompared to AdLib-microbiota recipients

    Effects of caloric restriction on the gut microbiome are linked with immune senescence

    Microbiome

Body fat accumulation

downin mice1

1 study
  1. Caloric restriction gut microbiota decreases body fat accumulation in mice.

    “Transplantation of CalRes-microbiota into mice decreased their body fat accumulation and improved glucose tolerance compared to AdLib-microbiota recipients.”

    Animalscompared to AdLib-microbiota recipients

    Effects of caloric restriction on the gut microbiome are linked with immune senescence

    Microbiome

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