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Body mass index variability

Exposure

1 paper1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

  • 1 lab in 1 country
  • 1 of 1 finding with company ties
  • Humans1

Outcomes

1

Cognitive function

downin humans1

1 study

  1. Body mass index variability impairs cognitive function in humans (β = -0.036 [95% CI: -0.044 to -0.028] z scores per year).

    “Participants in the highest SD variability quartile had the fastest cognitive decline (β = -0.036 [95% CI: -0.044 to -0.028] z scores per year) compared with the lowest variability BMI quartile”

    Humans11 yearsn = 4,304

    Variability in body weight and body composition and cognitive trajectories in older adults in the United States

    Obesity (Silver Spring, Md.)Jul 3, 2025

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