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Beta-hydroxy-beta-methylbutyrate + beta-alanine

Intervention

1 paper studies it1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

  • 1 lab in 1 country
  • Funder: Abbott Laboratories
  • 1 of 1 finding with company ties
  • Animals1

Outcomes

1

Absolute muscle force

upin mice1

1 study

  1. Beta-hydroxy-beta-methylbutyrate + beta-alanine increases absolute muscle force in mice (+11% absolute force; 88.6 ± 2.2 vs. 79.8 ± 2.4 mN).

    “At submaximal frequency of stimulation (20 Hz), EDL from mice fed HMB plus β-alanine showed an 11% increase in absolute force”

    Animals20 Hz submaximal stimulation; pre-sarcopenia modelextensor digitorum longus muscle8 weeksmales

    Cellular and Physiological Effects of Dietary Supplementation with β-Hydroxy-β-Methylbutyrate (HMB) and β-Alanine in Late Middle-Aged Mice

    PloS oneMar 8, 2016

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