Benzene + toluene + ethylbenzene + xylenes
1 paper studies it5 findings
Across all fields, 1 paper: none in people yet, 1 in animals
- 1 lab in 1 country
- Funders: Conselho Nacional de Desenvolvimento Científico e Tecnológico and 5 more
- Model organisms1
Outcomes
5Frailty
upin worms1
1 study
Frailty
upin worms1
Benzene + toluene + ethylbenzene + xylenes increase frailty in worms (Index above 0.5 on all assessment days).
“The Frailty Index analysis revealed elevated values (index above 0.5) on all days in the mixture group compared to the control and isolated groups.”
Model organismsCompared with control and individual-compound exposure groupsAirborne mixtureBenzene 0.9 ppm, toluene 40 ppm, ethylbenzene 25 ppm, xylenes 17 ppmSeven days of exposure
Chemosphere
Neuronal damage
upin worms1
1 study
Neuronal damage
upin worms1
Benzene + toluene + ethylbenzene + xylenes increase neuronal damage in worms (5%, 43%, and 25% increases on days 4, 7, and 10, respectively).
“damage to physiological and neuronal parameters on days 4 (26 % and 5 %), 7 (70 % and 43 %), and 10 (95 % and 25 %).”
Model organismsAirborne mixtureNeuronBenzene 0.9 ppm, toluene 40 ppm, ethylbenzene 25 ppm, xylenes 17 ppmSeven days of exposure
Chemosphere
Physiological damage
upin worms1
1 study
Physiological damage
upin worms1
Benzene + toluene + ethylbenzene + xylenes increase physiological damage in worms (26%, 70%, and 95% increases on days 4, 7, and 10, respectively).
“damage to physiological and neuronal parameters on days 4 (26 % and 5 %), 7 (70 % and 43 %), and 10 (95 % and 25 %).”
Model organismsAirborne mixtureBenzene 0.9 ppm, toluene 40 ppm, ethylbenzene 25 ppm, xylenes 17 ppmSeven days of exposure
Chemosphere
Mitochondrial function
downin worms1
1 study
Mitochondrial function
downin worms1
Benzene + toluene + ethylbenzene + xylenes impair mitochondrial function in worms (40%, 10%, and 5% decreases on days 4, 7, and 10, respectively).
“with decreased mobility and mitochondrial function on days 4 (15 % and 40 %), 7 (27 % and 10 %), and 10 (30 % and 5 %).”
Model organismsAirborne mixtureBenzene 0.9 ppm, toluene 40 ppm, ethylbenzene 25 ppm, xylenes 17 ppmSeven days of exposure
Chemosphere
Mobility
downin worms1
1 study
Mobility
downin worms1
Benzene + toluene + ethylbenzene + xylenes impair mobility in worms (15%, 27%, and 30% decreases on days 4, 7, and 10, respectively).
“with decreased mobility and mitochondrial function on days 4 (15 % and 40 %), 7 (27 % and 10 %), and 10 (30 % and 5 %).”
Model organismsAirborne mixtureBenzene 0.9 ppm, toluene 40 ppm, ethylbenzene 25 ppm, xylenes 17 ppmSeven days of exposure
Chemosphere