BC-006

Intervention

1 paper3 findings

  • 1 lab
  • Animals1

Outcomes

3

Food intake

no changein cynomolgus monkeys1

1 study
  1. BC-006 has no effect on food intake in cynomolgus monkeys.

    “without significant impact on food intake”

    Animalsobese cynomolgus monkeys10 mg/kg sc

    Prevention of Weight Rebound and Restoration of Muscle Mass after Semaglutide Withdrawal Using Bc-006, an INHBE siRNA, in a Nonhuman Primate Obesity Model

    ADA Scientific Sessions 2026 abstract5 Jun 2026

Lean mass

upin cynomolgus monkeys1

1 study
  1. BC-006 increases lean mass in cynomolgus monkeys.

    “restored lean mass”

    Animalsafter semaglutide withdrawal10 mg/kg sc

    Prevention of Weight Rebound and Restoration of Muscle Mass after Semaglutide Withdrawal Using Bc-006, an INHBE siRNA, in a Nonhuman Primate Obesity Model

    ADA Scientific Sessions 2026 abstract5 Jun 2026

Fat mass

downin cynomolgus monkeys1

1 study
  1. BC-006 decreases fat mass in cynomolgus monkeys.

    “BC-006 prevented weight rebound (Fig. 1A) and fat mass regain”

    Animalsafter semaglutide withdrawal10 mg/kg sc

    Prevention of Weight Rebound and Restoration of Muscle Mass after Semaglutide Withdrawal Using Bc-006, an INHBE siRNA, in a Nonhuman Primate Obesity Model

    ADA Scientific Sessions 2026 abstract5 Jun 2026

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