Autologous ipsc-derived retinal pigment epithelium sheet
Intervention1 paper2 findings
- Human trial1
Outcomes
1Outer nuclear layer
downin humans1Very low certainty
1 study
Outer nuclear layer
downin humans1Very low certainty
Autologous ipsc-derived retinal pigment epithelium sheet protects against outer nuclear layer in humans.
Human trialneovascular age-related macular degenerationretina10-year
Ten-Year Survival of First-in-Human Autologous Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelium Sheet Transplantation · Ophthalmology. Retina · 16 Sep 2026
Associations
1Subretinal pigmentation
upin humans1Very low certainty
1 study
Subretinal pigmentation
upin humans1Very low certainty
Autologous ipsc-derived retinal pigment epithelium sheet is associated with subretinal pigmentation in humans.
Human trialneovascular age-related macular degenerationsubretinal space10-year
Ten-Year Survival of First-in-Human Autologous Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelium Sheet Transplantation · Ophthalmology. Retina · 16 Sep 2026