Atomoxetine
- 2 independent labs in 2 countries
- Funders: Canadian Institutes of Health Research and 3 more
- Human trial1
- Animals1
Outcomes
6Conscious error awareness
no changein humans1
1 study
Conscious error awareness
no changein humans1
Atomoxetine has no effect on conscious error awareness in humans.
“there were no significant differences in conscious error awareness between atomoxetine and placebo.”
Human trialhealthy older adultsn = 30
Biological psychiatry. Cognitive neuroscience and neuroimaging9 Jun 2026
Pupil dilation
downin humans1
1 study
Pupil dilation
downin humans1
Atomoxetine decreases pupil dilation in humans.
“Atomoxetine reduced phasic pupil dilation to both novel stimuli in the novelty-oddball task and to action errors in the antisaccade task.”
Human trialhealthy older adultsn = 30
Biological psychiatry. Cognitive neuroscience and neuroimaging9 Jun 2026
Long-term depression
downin rats1
1 study
Long-term depression
downin rats1
Atomoxetine prevents long-term depression in rats.
“ATM administration ex vivo prevented PC LTD.”
Animalspiriform cortex
The European journal of neuroscience27 Dec 2024
Freezing behaviour
downin rats1
1 study
Freezing behaviour
downin rats1
Atomoxetine decreases freezing behaviour in rats.
“ATM resulted in less freezing behaviour in a threat conditioning and extinction paradigm at moderate, but not at higher doses.”
Animalsmoderate
The European journal of neuroscience27 Dec 2024
Reversal learning
downin rats1
1 study
Reversal learning
downin rats1
Atomoxetine impairs reversal learning in rats.
“hindered learning reversal.”
Animals
The European journal of neuroscience27 Dec 2024
Odour discrimination learning
upin rats1
1 study
Odour discrimination learning
upin rats1
Atomoxetine improves odour discrimination learning in rats.
“ATM improved reward-based odour discrimination in adults”
Animals
The European journal of neuroscience27 Dec 2024