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AR-C118925XX

Intervention

1 paper studies it3 findings

PubChem

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: Chiesi Farmaceutici and 2 more
  • Animals1

Outcomes

3

Endocortical bone formation

upin mice1

1 study

  1. AR-C118925XX increases endocortical bone formation in mice.

    “Endocortical bone formation also increased with treatment independently of exercise, providing gains in mechanical strength and tissue level properties.”

    Animalsindependently of exercise

    P2Y₂ Inhibition Modifies the Anabolic Response to Exercise in Adult Mice

    Aging cell

Osteoclast activity

downin mice1

1 study

  1. AR-C118925XX decreases osteoclast activity in mice.

    “The enhanced response to exercise was characterized by a reduction in osteocytes' induction of osteoclast activity.”

    Animalsin response to exercise

    P2Y₂ Inhibition Modifies the Anabolic Response to Exercise in Adult Mice

    Aging cell

Periosteal bone formation

upin mice1

1 study

  1. AR-C118925XX increases periosteal bone formation in mice.

    “ARC treatment of adult mice increases periosteal bone formation in response to exercise.”

    Animalsin response to exercise

    P2Y₂ Inhibition Modifies the Anabolic Response to Exercise in Adult Mice

    Aging cell

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