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Antimicrobial photodynamic therapy

Antimicrobial photodynamic therapy has been studied in 1 paper since 2022: none in people yet, 1 in animals. The research so far is in animals. The newest paper, Oct 23, 2022: “Effectiveness of antimicrobial photodynamic therapy mediated by butyl toluidine blue in preventing medication-related osteonecrosis of the jaws in rats”.

Intervention

1 paper studies it3 findingsUpdated

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: Conselho Nacional de Desenvolvimento Científico e Tecnológico and 2 more
  • Animals1

What did studies of Antimicrobial photodynamic therapy find?

3

Studies of Antimicrobial photodynamic therapy measured 3 outcomes; the most studied are percentage of non-vital bone tissue (1 study), percentage of newly formed bone tissue (1) and medication-related osteonecrosis of the jaw (1).

Percentage of non-vital bone tissue

downin rats1

1 study

  1. Antimicrobial photodynamic therapy decreases percentage of non-vital bone tissue in rats.

    “whereas PNVBT in the ZOL group was higher than in the VEH, VEH-aPDT and ZOL-aPDT groups.”

    Animalsin zoledronate-treated senescent rats after tooth extractionjawfemales

    Effectiveness of antimicrobial photodynamic therapy mediated by butyl toluidine blue in preventing medication-related osteonecrosis of the jaws in rats

    Photodiagnosis and photodynamic therapy

More on Percentage of non-vital bone tissue

Percentage of newly formed bone tissue

upin rats1

1 study

  1. Antimicrobial photodynamic therapy increases percentage of newly formed bone tissue in rats.

    “PNFBT in the ZOL group was lower than in the VEH, VEH-aPDT and ZOL-aPDT groups”

    Animalsin zoledronate-treated senescent rats after tooth extractionjawfemales

    Effectiveness of antimicrobial photodynamic therapy mediated by butyl toluidine blue in preventing medication-related osteonecrosis of the jaws in rats

    Photodiagnosis and photodynamic therapy

More on Percentage of newly formed bone tissue

Medication-related osteonecrosis of the jaw

downin rats1

1 study

  1. Antimicrobial photodynamic therapy prevents medication-related osteonecrosis of the jaw in rats.

    “aPDT mediated by BuTB prevented the occurrence of MRONJ-like lesions after tooth extraction in rats.”

    Animalsafter tooth extraction in zoledronate-treated senescent ratsjawfemales

    Effectiveness of antimicrobial photodynamic therapy mediated by butyl toluidine blue in preventing medication-related osteonecrosis of the jaws in rats

    Photodiagnosis and photodynamic therapy

More on Medication-related osteonecrosis of the jaw

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