Antigen exposure
1 paper1 finding
- 1 lab in 1 country
- Funders: Digestive Diseases Research Core Center, University of Chicago and 4 more
- Animals1
Outcomes
1Age-associated GZMK+CD8+ T cell development
is required forin mice1
1 study
Age-associated GZMK+CD8+ T cell development
is required forin mice1
Antigen exposure is required for age-associated GZMK+CD8+ T cell development in mice.
“TAA cell development is cell extrinsic and requires antigen exposure within aged non-lymphoid tissues.”
Animalsnon-lymphoid tissue
Inflammaging in aged tissues drives remodeling of the CD8⁺ T cell compartment
Cell reportsApr 22, 2026
Latest
1 in 12 monthsCell Reports
Inflammaging in aged tissues drives remodeling of the CD8⁺ T cell compartment
Experiments in miceInflammation