ANTI-FGF23 antibody

Intervention

1 paper1 finding

  • 1 lab in 2 countries
  • Funders: Berlin Institute of Health and 4 more
  • Animals1

Outcomes

1

Pulmonary vascular remodelling

downin mice1

1 study
  1. ANTI-FGF23 antibody prevents pulmonary vascular remodelling in mice.

    “FGF23 neutralisation using an anti-FGF23 antibody reduced RVSP, improved RV dysfunction and RV hypertrophy and prevented pulmonary vascular remodelling.”

    Animalsin kl/+ mice under hypoxia14 days

    Dysregulated Klotho and FGF23 signalling aggravates vascular remodelling in age-related pulmonary hypertension

    Cardiovascular research27 Feb 2026

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