Plasma levels of FGF23

1. KL increases plasma levels of FGF23 in mice.

   “Aged mice and kl/+ mice had elevated plasma levels of FGF23, further amplified by hypoxic exposure.”

   Animalsin kl/+ mice

   Dysregulated Klotho and FGF23 signalling aggravates vascular remodelling in age-related pulmonary hypertension

   Cardiovascular research·27 Feb 2026

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