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Alsterpaullone

Intervention

1 paper studies it3 findings

PubChemChEBI

Across all fields, 1 paper: none in people yet, 1 in animals

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 2 countries
  • Model organisms1

Outcomes

3

Egg maturation

downin H. oligactis1

1 study

  1. Alsterpaullone decreases egg maturation in H. oligactis.

    “We found that ALP delayed egg maturation when applied in early stages”

    Model organismsearly stages of gametogenesis

    Canonical Wnt/β-catenin signalling regulates inducible aging and regeneration loss in hydra

    bioRxiv (Cold Spring Harbor Laboratory)Preprint

Lifespan

upin H. oligactis1

1 study

  1. Alsterpaullone extends lifespan in H. oligactis.

    “ALP treatment increased survival following sexual reproduction.”

    Model organismsin post-reproductive sexual polyps

    Canonical Wnt/β-catenin signalling regulates inducible aging and regeneration loss in hydra

    bioRxiv (Cold Spring Harbor Laboratory)Preprint

Regeneration

upin H. oligactis1

1 study

  1. Alsterpaullone improves regeneration in H. oligactis.

    “Pharmacological activation of canonical Wnt/β-catenin signalling with alsterpaullone (ALP) restored head regeneration and improved survival of animals.”

    Model organismsin post-reproductive sexual polyps

    Canonical Wnt/β-catenin signalling regulates inducible aging and regeneration loss in hydra

    bioRxiv (Cold Spring Harbor Laboratory)Preprint

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