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Aldosterone receptor antagonist

Intervention

1 paper2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funder: Japan Society for the Promotion of Science
  • Animals1

Outcomes

2

Average life span

upin rats1

1 study

  1. Aldosterone receptor antagonist extends average life span in rats.

    “and lengthened the average life span in LP offspring in response to the drinking of 1% saline.”

    Animalsin response to 1% saline drinking in LP offspring

    Role of the renin-angiotensin-aldosterone system in the enhancement of salt sensitivity caused by prenatal protein restriction in stroke-prone spontaneously hypertensive rats

    The Journal of nutritional biochemistry19 Sep 2011

Blood pressure

downin rats1

1 study

  1. Aldosterone receptor antagonist prevents blood pressure in rats.

    “Treatment of the LP offspring with an aldosterone receptor antagonist prevented the blood pressure from elevating”

    Animalsin response to 1% saline drinking in LP offspring

    Role of the renin-angiotensin-aldosterone system in the enhancement of salt sensitivity caused by prenatal protein restriction in stroke-prone spontaneously hypertensive rats

    The Journal of nutritional biochemistry19 Sep 2011

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