AIN-76A diet

Intervention

1 paper2 findings

  • 1 lab in 1 country
  • Funder: National Institutes of Health
  • Animals1

Outcomes

1

Lifespan

downin mice1

1 study
  1. AIN-76A diet shortens lifespan in mice.

    “males and females fed purified diet (AIN-fed) gained weight more rapidly, attained higher maximum body weights, and died earlier than their non-purified diet (NIH-fed) counterparts.”

    Animalsspontaneous (without 2-AAF)up to 2 years

    Effects of diet type on incidence of spontaneous and 2-acetylaminofluorene-induced liver and bladder tumors in BALB/c mice fed AIN-76A diet versus NIH-07 diet

    Fundamental and applied toxicology : official journal of the Society of Toxicology1 Feb 1992

Associations

1

Liver tumors

upin mice1

1 study
  1. AIN-76A diet raises the risk of liver tumors in mice.

    “the AIN diet was clearly associated with a higher spontaneous frequency of liver neoplasia than the NIH diet.”

    Animalsspontaneous neoplasialiverup to 2 yearsmales

    Effects of diet type on incidence of spontaneous and 2-acetylaminofluorene-induced liver and bladder tumors in BALB/c mice fed AIN-76A diet versus NIH-07 diet

    Fundamental and applied toxicology : official journal of the Society of Toxicology1 Feb 1992

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