Aged rat serum

Aged rat serum has been studied in 1 paper since 2024: none in people yet, 1 in cells. No study of it in people or animals has been published yet. The newest paper, Oct 15, 2024: “Cellular and transcriptomic changes by the supplementation of aged rat serum in human pluripotent stem cell-derived myogenic progenitors”.

Intervention

1 paper studies it3 findingsUpdated

See all 1 papers on aged rat serum

At a glance

The findings reach cells, none yet in people. 1 lab in 1 country.

None of its findings points the other way.

Cells: a single group. Worms or flies, mice and humans: nothing yet.
  • 1 lab in 1 country
  • Funders: Good Food Institute and 6 more
  • Cells1

What did studies of aged rat serum find?

3

Studies of aged rat serum measured 3 outcomes; the most studied are myotube formation (1 study), cell death (1) and cell proliferation (1).

Myotube formation

downin human cells1

1 study
  1. Aged rat serum inhibits myotube formation in human cells (compared to young adult rat serum).

    “supplementation of aged rat serum inhibited myotube formation and maturation during terminal differentiation from progenitors to skeletal myocytes”

    Cellscompared to young adult rat serum

    Cellular and transcriptomic changes by the supplementation of aged rat serum in human pluripotent stem cell-derived myogenic progenitors

    Frontiers in cell and developmental biology

Cell death

upin human cells1

1 study
  1. Aged rat serum induces cell death in human ESC- and iPSC-derived myogenic progenitors.

    “aged rat serum supplementation significantly reduced cell proliferation and increased cell death in both ESC- and iPSC-derived myogenic progenitors”

    Cellsin human ESC- and iPSC-derived myogenic progenitors

    Cellular and transcriptomic changes by the supplementation of aged rat serum in human pluripotent stem cell-derived myogenic progenitors

    Frontiers in cell and developmental biology

Cell proliferation

downin human cells1

1 study
  1. Aged rat serum decreases cell proliferation in human ESC- and iPSC-derived myogenic progenitors.

    “aged rat serum supplementation significantly reduced cell proliferation and increased cell death in both ESC- and iPSC-derived myogenic progenitors”

    Cellsin human ESC- and iPSC-derived myogenic progenitors

    Cellular and transcriptomic changes by the supplementation of aged rat serum in human pluripotent stem cell-derived myogenic progenitors

    Frontiers in cell and developmental biology

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