Aerobic-resistance exercise + cognitive training
Aerobic-resistance exercise + cognitive training has been studied in 2 papers since 2025: 2 trials in people; 2 in the past year. The newest paper, Jan 30, 2026: “The effect of hearing ability on dual-task performance following multi-domain training in older adults with mild cognitive impairment: findings from the SYNERGIC trial”.
2 papers study it3 findingsUpdated
“Exercise plus cognitive training showed the greatest gains in gait speed and reduced injurious falls (IRR=0.13, p = 0.05).”
None of its findings points the other way.
- 2 independent labs in 1 country
- Funder: Gouvernement du Canada | Canadian Institutes of Health Research
- 2 of 3 findings with company ties
- Human trial2
Studies in people
2 studies gave aerobic-resistance exercise + cognitive training to people and measured what changed.
down: Decreases dual-task gait variabilityΔ = −0.54% CoV
Randomized trial75 peopleBothMage = 73.66 years ± 6.6720 weeks
Older adults between 60 and 85 years old with mild cognitive impairment
Frontiers in aging neuroscience, Jan 30, 2026
down: Decreases injurious fallsIRR=0.13
Randomized trial161 peopleolder adults20 weeks
Older adults; in older adults with MCI
GSA 2025 abstract, Dec 31, 2025
What did studies of Aerobic-resistance exercise + cognitive training find?
3Studies of Aerobic-resistance exercise + cognitive training measured 3 outcomes; the most studied are dual-task gait variability (1 study), dual-task gait variability (1) and injurious falls (1).
Dual-task gait variability
downin humans1
1 study
Dual-task gait variability
downin humans1
Aerobic-resistance exercise + cognitive training decreases dual-task gait variability in humans (Δ = −0.54% CoV).
“Specifically, in participants with a greater degree of hearing complaints (i.e., higher HHIE-S scores), there was a significant reduction (i.e., improvement) in dual-task stride time variability only following Multi-Domain Training, Δ = −0.54% CoV, SE = 0.21, p = 0.01.”
Human trialin participants with a greater degree of hearing complaints20 weeksn = 32
Frontiers in aging neuroscience
Dual-task gait variability
downin humans1
1 study
Dual-task gait variability
downin humans1
Aerobic-resistance exercise + cognitive training decreases dual-task gait variability in humans.
“Dual-task gait variability significantly improved following Multi-Domain Training in participants with a greater degree of self-reported hearing complaints.”
Human trialin participants with a greater degree of self-reported hearing complaints20-weekn = 32
Frontiers in aging neuroscience
Injurious falls
downin humans1
1 study
Injurious falls
downin humans1
Aerobic-resistance exercise + cognitive training decreases injurious falls in humans (IRR=0.13).
“Exercise plus cognitive training showed the greatest gains in gait speed and reduced injurious falls (IRR=0.13, p = 0.05).”
Human trialin older adults with MCI20 weeks
Synergic trial secondary outcomes results on gait and falls
GSA 2025 abstract