Adipose-derived stem cell / endothelial colony-forming cell 3d co-culture
Adipose-derived stem cell / endothelial colony-forming cell 3d co-culture has been studied in 1 paper since 2020: none in people yet, 1 in animals. The research so far is in animals. The newest paper, Aug 14, 2020: “3D co-culture model of endothelial colony-forming cells (ECFCs) reverses late passage adipose-derived stem cell senescence for wound healing”.
1 paper studies it4 findingsUpdated
See all 1 papers on adipose-derived stem cell / endothelial colony-forming cell 3d co-culture
At a glance
The findings reach mice, none yet in people. 1 lab in 1 country.
None of its findings points the other way.
- 1 lab in 1 country
- Funders: Nanfang Hospital and 2 more
- Animals1
What did studies of adipose-derived stem cell / endothelial colony-forming cell 3d co-culture find?
4Studies of adipose-derived stem cell / endothelial colony-forming cell 3d co-culture measured 4 outcomes, among them angiogenesis, wound healing and hepatocyte growth factor.
Angiogenesis
upin mice1
1 study
Angiogenesis
upin mice1
Adipose-derived stem cell / endothelial colony-forming cell 3d co-culture increases angiogenesis in mice (transplanted into radiation-ulcer wounds).
“transplanted ASC/ECFC spheroids exhibited superior angiogenic potential due to the ability of the ASCs to transdifferentiate into pericytes”
Animalstransplanted into radiation-ulcer wounds3D spheroidsskin
Stem cell research & therapy
Wound healing
upin mice1
1 study
Wound healing
upin mice1
Adipose-derived stem cell / endothelial colony-forming cell 3d co-culture improves wound healing in mice (radiation-ulcer wound model; compared with ASCs or ECFCs alone).
“Mice radiation-ulcer wounds treated with ASC/ECFC 3-D co-cultures (spheroids) showed epithelialization and improved healing compared with wounds treated with ASCs or ECFCs alone”
Animalsradiation-ulcer wound model; compared with ASCs or ECFCs alone3D spheroidsskin
Stem cell research & therapy
Hepatocyte growth factor
upin human cells1
1 study
Hepatocyte growth factor
upin human cells1
Adipose-derived stem cell / endothelial colony-forming cell 3d co-culture increases hepatocyte growth factor in human cells (compared with single-cell 3D culture or monolayer culture).
“The ASC/ECFC co-culture increased the secretion of cytokines, such as hepatocyte growth factor, compared with single-cell 3D culture or monolayer culture”
Cellscompared with single-cell 3D culture or monolayer culture
Stem cell research & therapy
Cellular senescence
downin human cells1
1 study
Cellular senescence
downin human cells1
Adipose-derived stem cell / endothelial colony-forming cell 3d co-culture decreases cellular senescence in human cells (late-passage ASCs, hyaluronic acid 3D co-culture).
“3D co-culture of ECFCs and ASCs in vitro restored native ASC properties by reversing cellular senescence and loss of trophic function”
Cellslate-passage ASCs, hyaluronic acid 3D co-culture
Stem cell research & therapy