Adenovirus encoding mt-iii gene

Adenovirus encoding mt-iii gene increases duration of illness in mice (25.71±7.67 days vs 15.20±5.30 and 10.33±4.27 days).

“mean durations of illness were 15.20±5.30 days, 10.33±4.27 days, and 25.71±7.67 days in the untreated group, LacZ group, and MT-III group”

AnimalsG93A SOD-1 mutant-transgenic mice

Metallothionein-III prevents neuronal death and prolongs life span in amyotrophic lateral sclerosis model mice

Neuroscience·30 May 2011

Adenovirus encoding mt-iii gene extends lifespan in mice (178.14±12.97 days vs 163.20±7.72 and 159.50±3.27 days).

“MT-III prevents the loss of motor neurons of ALS model mice and prolongs the life span”

AnimalsG93A SOD-1 mutant-transgenic mice

Metallothionein-III prevents neuronal death and prolongs life span in amyotrophic lateral sclerosis model mice

Neuroscience·30 May 2011

Adenovirus encoding mt-iii gene decreases loss of motor neurons in mice (24.75±4.01 vs 15.42±5.32 and 16.50±1.35 neurons).

“MT-III prevents the loss of motor neurons of ALS model mice”

AnimalsG93A SOD-1 mutant-transgenic micelumbar spinal cord

Metallothionein-III prevents neuronal death and prolongs life span in amyotrophic lateral sclerosis model mice

Neuroscience·30 May 2011