Active brains

Intervention1 paper1 finding

Human trial1

Outcomes

1

Baddeley verbal reasoning score

upin humans1Moderate certainty

1 study

Active brains improve baddeley verbal reasoning score in humans (adjusted mean difference +0·50, 95% CI 0·13-0·87).
Human trialage-associated cognitive decline12 monthsn = 3,810
A digital intervention to protect cognitive health in older adults with cognitive impairment: a three-arm, open-label, randomised controlled trial · The Lancet. Primary care · 1 Aug 2026

Funding

National Institute on AgingUS$594.7k1 grant since 2022

Addressing the chronic pain-early cognitive decline comorbidity among older adults; The Active Brains study
National Institute on AgingMassachusetts General HospitalUS$594.7k2022–2027

Latest

1

The Lancet Primary CareHuman trial9 Sep

A digital intervention to protect cognitive health in older adults with cognitive impairment: a three-arm, open-label, randomised controlled trial

Mild cognitive impairment