2,3-dihydro-3,5-dihydroxy-6-methyl-4h-pyran-4-one
2,3-dihydro-3,5-dihydroxy-6-methyl-4h-pyran-4-one has been studied in 1 paper since 2025: 1 trial in people. The newest paper, Jan 1, 2025: “Effect of Probiotic Drinks Containing 2,3-Dihydro-3,5-dihydroxy-6-methyl-4H-pyran-4-one on Cognitive Function of Middle-Aged and Older Individuals”.
“verbal and composite memory scores were considerably higher in the DDMP group than in the placebo group”
None of its findings points the other way.
- 1 lab in 1 country
- 2 of 2 findings with company ties
- Human trial1
Studies in people
1 study gave 2,3-dihydro-3,5-dihydroxy-6-methyl-4h-pyran-4-one to people and measured what changed.
up: Improves cognitive function
Randomized trial220 peoplemiddle-aged and older12 wk
Midlife adults; Older adults; memory decline
Journal of nutritional science and vitaminology, Jan 1, 2025
What did studies of 2,3-dihydro-3,5-dihydroxy-6-methyl-4h-pyran-4-one find?
2Studies of 2,3-dihydro-3,5-dihydroxy-6-methyl-4h-pyran-4-one measured 2 outcomes; the most studied are oxidative stress and ROS signaling (1 study) and cognitive function (1).
Oxidative stress and ROS signaling
no changein humans1
1 study
Oxidative stress and ROS signaling
no changein humans1
2,3-dihydro-3,5-dihydroxy-6-methyl-4h-pyran-4-one showed no clear effect on oxidative stress and ROS signaling in humans (memory decline).
“no significant differences in oxidative stress markers were noticed”
Human trialmemory declinelactic acid bacteria beverage2.2 mg DDMP in 65 mL LAB beverage daily12 wkn = 220
Journal of nutritional science and vitaminology
Cognitive function
upin humans1
1 study
Cognitive function
upin humans1
2,3-dihydro-3,5-dihydroxy-6-methyl-4h-pyran-4-one improves cognitive function in humans (memory decline).
“verbal and composite memory scores were considerably higher in the DDMP group than in the placebo group”
Human trialmemory declinelactic acid bacteria beverage2.2 mg DDMP in 65 mL LAB beverage daily12 wkn = 220
Journal of nutritional science and vitaminology