AgingResearch.NewsJoin free

ZNF518A

Gene

1 paper2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab
  • Humans1

Associations

2

Age at menarche

upin humans1

1 study

  1. ZNF518A is associated with age at menarche in humans.

    “later puberty timing in girls (age at menarche, 0.56 years [0.15-0.97], P =9.2*10 -3 )”

    Humansprotein truncating variantsfemales

    Genetic susceptibility to earlier ovarian ageing increases de novo mutation rate in offspring

    medRxiv23 Jun 2022Preprint

Age at natural menopause

downin humans1

1 study

  1. ZNF518A is associated with age at natural menopause in humans.

    “earlier age at natural menopause (ANM, 5.61 years [4.04-7.18], P =2*10 -12 )”

    Humansprotein truncating variantsfemales

    Genetic susceptibility to earlier ovarian ageing increases de novo mutation rate in offspring

    medRxiv23 Jun 2022Preprint

Latest

Related