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TERC-53

Gene

1 paper4 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: Jinan University and 3 more
  • Animals1

Effects

4

Inflammation

upin mice1

1 study

  1. TERC-53 increases inflammation in mice.

    “leading to an increase of inflammation in the affected tissues, accelerating organismal aging.”

    Animalsoverexpression of Terc-53

    Noncoding RNA Terc-53 and hyaluronan receptor Hmmr regulate aging in mice

    Protein & cell4 Jan 2025

More on Inflammation

HMMR

downin mice1

1 study

  1. TERC-53 decreases HMMR in mice.

    “Terc-53 mediates the degradation of Hmmr”

    Animalsoverexpression of Terc-53

    Noncoding RNA Terc-53 and hyaluronan receptor Hmmr regulate aging in mice

    Protein & cell4 Jan 2025

More on HMMR

Cognitive function

downin mice1

1 study

  1. TERC-53 impairs cognitive function in mice.

    “Terc-53 mice showed age-related cognition decline and shortened life span”

    Animalsoverexpression of Terc-53

    Noncoding RNA Terc-53 and hyaluronan receptor Hmmr regulate aging in mice

    Protein & cell4 Jan 2025

Lifespan

downin mice1

1 study

  1. TERC-53 shortens lifespan in mice.

    “Terc-53 mice showed age-related cognition decline and shortened life span”

    Animalsoverexpression of Terc-53

    Noncoding RNA Terc-53 and hyaluronan receptor Hmmr regulate aging in mice

    Protein & cell4 Jan 2025

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