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SSTR2

There is 1 paper on SSTR2 in aging research: none in people yet, 1 in animals.

Gene

1 paper studies it1 finding

HGNCNCBI GeneTaxon

See all 1

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • 2 trials
  • Funders: Centre National de la Recherche Scientifique and 1 more
  • 2 of 2 trials sponsored by developers of drugs on it
  • Animals1

Effects

1

Circulating corticosterone

downin mice1

1 study

  1. SSTR2 decreases circulating corticosterone in mice (shown by gene deletion).

    “the deletion of the sst2 receptor gene produces chronic hypercorticosteronemia”

    Animalsshown by gene deletion

    sst₂-receptor gene deletion exacerbates chronic stress-induced deficits: Consequences for emotional and cognitive ageing

    Progress in neuro-psychopharmacology & biological psychiatry

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