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Ssk

Gene

1 paper studies it1 finding

Taxon

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: Biotechnology and Biological Sciences Research Council and 5 more
  • Model organisms1

Effects

1

Epithelial barrier function

is required forin flies1

1 study

  1. Ssk is required for epithelial barrier function in flies.

    “Acute loss of the SJ protein Snakeskin in adult tubules induced progressive changes in cellular and tissue architecture, including altered expression and localisation of junctional proteins with concomitant loss of cell polarity and barrier integrity”

    Model organismsacute loss in adult tubulesMalpighian tubule

    Compromised junctional integrity phenocopies age-dependent renal dysfunction in Drosophila Snakeskin mutants

    Journal of cell science

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