sl

Gene

3 papers study it6 findings

Taxon

  • 1 lab in 1 country
  • Funders: Huffington Foundation and others
  • Humans2
  • Model organisms1

Effects

2

Locomotor function

downin flies3

3 studies
  1. sl impairs locomotor function in flies.

    “We document that mutant flies also exhibit a reduced lifespan and age-dependent locomotor defects.”

    Model organismsin slT2A null mutant flies

    Heterozygous variants in PLCG1 affect hearing, vision, cardiac, and immune function

    eLife

  2. sl impairs locomotor function in flies.

    “We document that mutant flies also exhibit a reduced lifespan and age-dependent locomotor defects.”

    Model organismsslT2A mutant

    Heterozygous variants in PLCG1 affect hearing, vision, cardiac, and immune function

    eLifePreprint

  3. sl impairs locomotor function in flies.

    “We document that mutant flies exhibit a reduced lifespan and age-dependent locomotor defects.”

    Model organismsin sl null mutant flies (slT2A)

    De novo variants in PLCG1 are associated with hearing impairment, ocular pathology, and cardiac defects

    eLifePreprint

Lifespan

downin flies3

3 studies
  1. sl decreases lifespan in flies.

    “We document that mutant flies also exhibit a reduced lifespan and age-dependent locomotor defects.”

    Model organismsin slT2A null mutant flies

    Heterozygous variants in PLCG1 affect hearing, vision, cardiac, and immune function

    eLife

  2. sl shortens lifespan in flies.

    “We document that mutant flies also exhibit a reduced lifespan and age-dependent locomotor defects.”

    Model organismsslT2A mutant

    Heterozygous variants in PLCG1 affect hearing, vision, cardiac, and immune function

    eLifePreprint

  3. sl shortens lifespan in flies.

    “We document that mutant flies exhibit a reduced lifespan and age-dependent locomotor defects.”

    Model organismsin sl null mutant flies (slT2A)

    De novo variants in PLCG1 are associated with hearing impairment, ocular pathology, and cardiac defects

    eLifePreprint

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