RS9640883
1 paper2 findings
- 1 lab in 2 countries
- 1 finding against
- Funder: Wellcome Trust
- Humans1
Effects
1Cortical cataract
no changein humans1OR 0.85
1 study
Cortical cataract
no changein humans1OR 0.85
RS9640883 has no effect on cortical cataract in humans (OR 0.85, 95% CI 0.69-1.04).
“No similar association was found in participants with normal FBG (OR 0.85, 95% CI 0.69-1.04).”
Humansin participants with normal FBG
Aldose Reductase Polymorphisms, Fasting Blood Glucose, and Age-Related Cortical Cataract
Investigative ophthalmology & visual science4 Sep 2018
Associations
1Cortical cataract
upin humans1OR 1.72
1 study
Cortical cataract
upin humans1OR 1.72
RS9640883 raises the risk of cortical cataract in humans (OR 1.72, 95% CI 1.09-2.72).
“increased cortical cataract prevalence associated with rs9640883 minor allele dosage in those with FBG >6.0 mM (strata-specific OR 1.72, 95% CI 1.09-2.72)”
Humansin those with FBG >6.0 mM
Aldose Reductase Polymorphisms, Fasting Blood Glucose, and Age-Related Cortical Cataract
Investigative ophthalmology & visual science4 Sep 2018
Latest
Investigative Ophthalmology & Visual Science
Aldose Reductase Polymorphisms, Fasting Blood Glucose, and Age-Related Cortical Cataract
Cross-sectional study of 10,033 peopleEye