RS9640883

Gene

1 paper2 findings

  • 1 lab in 2 countries
  • 1 finding against
  • Funder: Wellcome Trust
  • Humans1

Effects

1

Cortical cataract

no changein humans1OR 0.85

1 study
  1. RS9640883 has no effect on cortical cataract in humans (OR 0.85, 95% CI 0.69-1.04).

    “No similar association was found in participants with normal FBG (OR 0.85, 95% CI 0.69-1.04).”

    Humansin participants with normal FBG

    Aldose Reductase Polymorphisms, Fasting Blood Glucose, and Age-Related Cortical Cataract

    Investigative ophthalmology & visual science4 Sep 2018

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Associations

1

Cortical cataract

upin humans1OR 1.72

1 study
  1. RS9640883 raises the risk of cortical cataract in humans (OR 1.72, 95% CI 1.09-2.72).

    “increased cortical cataract prevalence associated with rs9640883 minor allele dosage in those with FBG >6.0 mM (strata-specific OR 1.72, 95% CI 1.09-2.72)”

    Humansin those with FBG >6.0 mM

    Aldose Reductase Polymorphisms, Fasting Blood Glucose, and Age-Related Cortical Cataract

    Investigative ophthalmology & visual science4 Sep 2018

More on Cortical cataract

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