ROBO4

There is 1 paper on ROBO4 in aging research: none in people yet, 1 in animals.

1 paper studies it1 finding

HGNC NCBI Gene Taxon

1 lab in 1 country

Funders: American Heart Association and 2 more

Animals1

Effects

1

Cellular senescence

downin mouse cells1

1 study

ROBO4 protects against cellular senescence in mouse cells (downregulation).
“Robo4 downregulation contributed to enhanced vulnerability to FC-induced senescence”
Cellsdownregulationcerebral endothelial cells
Iron overload induces cerebral endothelial senescence in aged mice and in primary culture in a sex-dependent manner
Aging cellSep 7, 2023

More on Cellular senescence

Funding

1 grant since 2017

US Department of Veterans Affairs

Metabolic implications of adipose arterial function: Role of Robo4 and AMPK
US Department of Veterans AffairsVA Salt Lake City Health Care System2014–2018

Latest

Aging CellSep 7

Iron overload induces cerebral endothelial senescence in aged mice and in primary culture in a sex-dependent manner

Experiments in miceCellular senescence